Randomized study of reduced-intensity chemotherapy combined with imatinib in adults with Ph-positive acute lymphoblastic leukemia.
Chalandon Y, Thomas X, Hayette S, et al. Blood, 125:3 711, Jun 2015
Randomized study showed that reduced-intensity chemotherapy combined with imatinib is associated with lower early mortality and higher CR rate compared to a standard chemotherapy-imatinib combination protocol in adults with Ph-positive acute lymphoblastic leukemia.